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Adjunct Assistant Professor MICHAEL ROSSBACH
Ph.D., University of Witten/Herdecke (2007); Diplom-Biochemiker (M.Sc.), Private University of Witten/Herdecke (2004); Vordiplom (B.Sc.), University of Bonn (2000)
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Institute of Reconstructive Neurobiology
Life and Brain Center
University of Bonn
Sigmund-Freud-Strabe 25
53127 Bonn
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Tel: (49) 228-6885-472
Fax: (49) 228-6885-471
Email: chmrm@nus.edu.sg |
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"Dr. Rossbach is currently a Research Scientist at the Institute of Reconstructive Neurobiology, Life & Brain Center, University of Bonn. He did his postdoctoral studies at the Genome Institute of Singapore, Stem Cell & Developmental Biology. He is also a lecturer at the German Institute for Science and Technology (GIST), at PSB Academy (TUV Sud Group, Germany) and partner of a Life Science company in Germany. Beside his academic background, Dr. Rossbach runs his own consulting business"
Research Interests
- stem cell and developmental biology, embryonic development
- interaction of transcription factors and transcription factor networks (gene expression profiles) from a biochemical and structural perspective (systems biology)
- protein-protein and protein-DNA/RNA interactions in stem cells and development (Zink-finger proteins)
- RNA mediated gene silencing pathways (gene regulation, e.g. dicer / microRNAs / siRNAs)
- tumor genesis, the role of oncogenes in development.
Selected Publications
 2009 Haupt, S., Robbach, M., Ladewig, J., Peitz, M., Koch, P., Brustle, O. (2009) From Bench to Screening - Industrialisierung pluripotenter Stammzellen. Laborwelt, 10. Jahrgang, Nr. 2/2009
2009 Michael Robbach (2009) Creative Innovation - Insights from neurobiology and economics and their implications for social decision-making. VS Publishers ISBN 3531166883
Zheng-Xu Wang, Christina Hui-Leng Teh, Caroline Man-Tee Chan, Ci Chu, Michael Rossbach, Galih Kunarso, Tahira Bee Allapitchay, Kee Yew Wong and Lawrence W. Stanton (2008) The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes. Stem Cells 2008 Aug 28 Epub
Rossbach, M. (2007) Dissecting RNA Mediated Gene Silencing Pathways in Murine Embryonic Stem Cells. PhD thesis. University of Witten/Herdecke, Germany, September 2007
Zheng-Xu Wang, Li Ling Kueh, Hui Leng The, Michael Rossbach, Linda Lim, Pin Li, Kee Yew Wong, Thomas Lufkin, Paul Robson, Lawrence W. Stanton (2006) Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells. Stem Cells 2007; 25: 2173-2182
Michael Rossbach, Oliver Daumke, Claudia Klinger, Alfred Wittinghofer, Michael Kaufmann (2005) Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold. BMC Structural Biology 2005, 5:7
Klinger, C., Rossbach, M., Howe, R., Kaufmann, M. (2003) Thermophile-specific proteins: The gene product of aq_1292 from Aquifex aeolicus is an NTPase. BMC Biochemistry 2003, 4:12
Mollenbeck, M., Postberg, J., Paeschke, K., Rossbach, M., Jonsson, F., Lipps, H.J. (2003) The end-replication machinery in spirotrichous ciliates. Proceedings of the International Conference on the Molecular Biology and Biotechnology of Ciliates and Anaerobic Protozoa.
Mollenbeck, M., Postberg, J., Paeschke, K., Rossbach, M., Jonnson, F., Lipps, H.J. (2003) The telomerase associated protein p43 is involved in anchoring telomerase in the nucleus. Journal of Cell Science 116, 1757-1761
Rossbach, M. (1998) The effects of heavy metals on transmembrane proton transport as studied on isolated thylakoids of Raphanus sativus Stiftung Jugend forscht, Hamburg, Germany & Dechema e.V.,BIOTECHNOLOGY 2000 - The World Congress on Biotechnology, Section Environmentas Biotechnology, Book II
von Randow, J., Rossbach, M. (1997) The effects of ultraviolet and radioactive radiation on transmembrane proton transport as studied on isolated thylakoids of Raphanus sativus. Stiftung Jugend forscht, Hamburg, Germany
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