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Assistant Professor XUE FENG
Postdoctoral fellow, 2005, The Wistar Institute,
Philadelphia, PA, USA; Ph.D., 2000, The Chinese University
of Hong Kong, Hong Kong SAR, China; B.Sc., B.Sc.Eng., 1993,
Tsinghua University, Beijing, China
Contact Information
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Department of Chemistry, NUS
3 Science Drive 3
Singapore 117543 |
Office: S8-05-05
Tel: (65) 6516-2848
Fax: (65) 6779-1691
E-mail: chmxf@nus.edu.sg |
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Research Interests
- Supramolecular chemistry and crystal engineering of hydrogen-bonded
molecular solids, design and control molecular assembly and packing
arrangement to generate crystals with specific properties as new
material and drugs.
- Structural biology of viruses by X-ray crystallography, molecular
modeling and electron microscopy, understanding protein structure
and its biological function for pharmaceutical application.
Representative Publications
 Xue, F. and Burnett, R.M.
(2005). Structure-based vector design: identification of neutralizing
epitopes of chimpanzee adenovirus C68 by crystal structure studies
of hexon. manuscript in preparation.
Xue, F. and Burnett, R.M.
(2004). Crystallization and preliminary structure studies of major
coat protein, hexon, of chimpanzee adenovirus 68. J. Struct. Bio.,
submitted.
Thaimattam, R., Xue, F.,
Sarma, J.A.R.P., Mak, T.C.W. and Desiraju, G.R. (2001). Inclusion
Compounds of Tetrakis(4-nitrophenyl)methane: C-H…O Networks,
Pseudopolymorphism, and Structural Transformations. J. Am. Chem.
Soc., 123(19), 4432-4445.
Jetti, R.K.R., Nangia, A.,
Xue, F. and Mak, T.C.W. (2001). Polar host-guest assembly mediated
by halogen…p interaction: inclusion complexes of 2,4,6-tris
(4-halophenoxy)- 1,3,5-triazine (halo = chloro, bromo) with trihalobenzene
(halo = bromo, iodo). Chem. Commun. (Cambridge, U. K.), (10), 919-920.
Xue, F. and Mak, T.C.W. (2000).
Channel- and layer-type anionic host structures in inclusion compounds
of urea, tetraalkylammonium terephthalate/trimesate and water. Acta
Crystallogr., Sect. B: Struct. Sci., B56(1), 142-154.
Xue, F. and Mak, T.C.W. (2000).
Hydrogen-bonded anionic layer structures constructed from 4,4'-biphenyldicarboxylate
and water molecules, and also with urea as an additional component.
J. Phys. Org. Chem., 13(7), 405-414.
Mak, T.C.W. and Xue, F. (2000).
Supramolecular Rosette Ribbon Constructed from Guanidinium and Hydrogen
Carbonate Ions in the Crystal Engineering of Hydrogen-Bonded Networks.
J. Am. Chem. Soc., 122(40), 9860-9861.
Jetti, R.K.R., Xue, F., Mak,
T.C.W. and Nangia, A. (2000). 2,4,6-Tris-4- (bromophenoxy)-1,3,5-triazine:
a hexagonal host framework assembled with robust Br...Br trimer
synthons. Cryst. Eng., 2(4), 215-224.
Jetti, R.K.R., Xue, F., Mak,
T.C.W. and Nangia, A. (2000). 4-Tritylbenzoic acid. A molecular
scaffold for wheel-and-axle host-guest inclusion compounds with
a supramolecular axis. Perkin 2, (6), 1223-1232.
Jetti, R.K.R., Thallapally,
P.K., Xue, F., Mak, T.C.W. and Nangia, A. (2000). Hexagonal Nanoporous
Host Structures Based on 2,4,6-Tris-(4-halophenoxy)-1,3,5-triazines
(Halo=Chloro, Bromo). Tetrahedron, 56(36), 6707-6719.
Mak, K.W., Xue, F., Mak,
T.C.W. and Chan, K.S. (1999). Electronic effects in reversible 1,2-rearrangement
of planar porphyrinato rhodium(III) alkyls. J. Chem. Soc., Dalton
Trans., (19), 3333-3334.
Li, Q., Xue, F. and Mak,
T.C.W. (1999). Crystalline Inclusion Compounds of Urea with Oxoboron
Components. Stabilization of the Elusive Dihydrogen Borate Anion
in a Hydrogen-Bonded Host Lattice. Inorg. Chem., 38(18), 4142-4145.
Yuen, M.S.M., Xue, F., Mak,
T.C.W. and Wong, H.N.C. (1998). On the absolute structure of optically
active neolignans containing a dihydrobenzo[b]furan skeleton. Tetrahedron,
54(41), 12429-12444.
Thaimattam, R., Shekhar Reddy,
D., Xue, F., Mak, T.C.W., Nangia, A. and Desiraju, G.R. (1998).
Molecular networks in the crystal structures of tetrakis(4-iodophenyl)methane
and (4-iodophenyl)triphenylmethane. New J. Chem., 22(2), 143-148.
Thaimattam, R., Reddy, D.S.,
Xue, F., Mak, T.C.W., Nangia, A. and Desiraju, G.R. (1998). Interplay
of strong and weak hydrogen bonding in molecular complexes of some
4,4'-disubstituted biphenyls with urea, thiourea and water. J. Chem.
Soc., Perkin Trans. 2, (8), 1783-1789.
Jetti, R.K.R., Kuduva, S.S.,
Reddy, D.S., Xue, F., Mak, T.C.W., Nangia, A. and Desiraju, G.R.
(1998). 4-(Triphenylmethyl)benzoic acid: a supramolecular wheel-and-axle
host compound. Tetrahedron Lett., 39(8), 913-916.
Leung, W.-P., Kwok, W.-H.,
Xue, F. and Mak, T.C.W. (1997). Synthesis and Crystal Structure
of an Unprecedented Tin(II)-Tin(II) Donor-Acceptor Complex, RN2Sn?SnCl2
[RN = CH(SiMe3)C9H6N8-]. J. Am. Chem. Soc., 119(5), 1145-1146.
Zhang, H., Xue, F., Mak,
T.C.W. and Chan, K.S. (1996). Enantioselectivity Increases with
Reactivity: Electronically Controlled Asymmetric Addition of Diethylzinc
to Aromatic Aldehydes Catalyzed by a Chiral Pyridylphenol. J. Org.
Chem., 61(23), 8002-8003.
Xue, F. and Mak, T.C.W. (1996).
Supramolecular framework adducts constructed of hexamethylenetetramine,
aquated alkali metal cationic clusters, and hexacyanoferrates(II/III).
Struct. Chem., 7(4), 253-261.
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