Lecturer LIU Mei Hui

Assistant Dean (Student Life)



BSc (Hons), National University of Singapore, Food Science and Technology, 2003;  Ph.D. , National  University of Singapore (Molecular Biology), 2007; Visiting Fellow, Cornell University, 2010; Postdoctoral Fellow, Genome Institute of Singapore, 2007-2013
A*STAR Graduate Scholar (2004); A*STAR Postdoctoral Fellow (2010)

 

Contact Information

Office: S14-06-04
Tel: (65)-6516-3523 | Fax: (65)-6779-1691
Email: chmlmh@nus.edu.sg


Research Interests

  • Molecular Nutrition- Diet induced transcription regulation of Nuclear Receptors, their co-regulators and non-coding RNAs in clinically relevant pathways using Genomics and Molecular approaches
  • Nutrigenetics- Modulation of individual susceptibility to insulin resistance
  • Nutrigenomics- Stratified nutritional strategies for the Asian population

 

Teaching Contributions

  • FST2201 Introduction to Human Nutrition
  • FST3202 Nutrition and Disease Prevention
  • FST4202 Advanced Food Processing Technologies
  • GEK1529/GEH1019 Food and Health

 

Representative Publications

  • Liu, M. H.; Cheung, E. Systems Biology of Nuclear Hormone Signalling and Gene Regulation. In Signaling Gene Regulation and Cancer; Singh, S.R.; Mishra, M.K., Ed.; Nova Science Publishers Inc.: New York, 2012; pp 173-198.
  • Mason, C. E.; Shu, F. J.; Wang, C.; Session, R. M.; Kallen, R. G.; Sidell, N.; Yu, T. W.; Liu, M. H.; Cheung, E.; Kallen, C. B. Location Analysis for the Estrogen Receptor-Alpha Reveals Binding to Diverse ERE Sequences and Widespread Binding within Repetitive DNA Elements. Nucleic Acids Res. 2010, 38, 2355-2368.
  • Fullwood, M. J.; Liu, M. H.; Pan, Y. F. et al. An Estrogen-Receptor-Alpha-Bound Human Chromatin Interactome. Nature 2009, 462, 58-64.
  • Pan, Y. F.; Wansa, K. D.; Liu, M. H.; Zhao, B.; Hong, S. Z.; Tan, P. Y.; Lim, K. S.; Bourque, G.; Liu, E. T.; Cheung, E. Regulation of Estrogen Receptor-Mediated Long Range Transcription via Evolutionarily Conserved Distal Response Elements. J. Biol. Chem. 2008, 283, 32977- 32988.
  • Yong, E. L.; Li, J.; Liu, M. H. Single Gene Contributions: Genetic Variants of Peroxisome Proliferator-Activated Receptor (Isoforms Alpha, Beta/Delta and Gamma) and Mechanisms of Dyslipidemias. Curr. Opin. Lipidol. 2008, 19, 106-112.
  • Liu, M. H.; Li, J.; Shen, P.; Tai, E. S.; Yong, E. L. A Natural Polymorphism in Peroxisome Proliferator-Activated Receptor-Alpha Hinge Region Attenuates Transcription due to Defective Release of Nuclear Receptor Corepressor from Chromatin. Mol. Endocrinol. 2008, 22, 1078-1092.
  • Shen, P.; Liu, M. H.; Ng, T. Y.; Chan, Y. H.; Yong, E. L. Differential Effects of Isoflavones, from Astragalus Membranaceus and Pueraria Thomsonii, on the Activation of PPARα, PPARγ, and Adipocyte Differentiation In Vitro. J. Nutr. 2006, 136, 899-905.
  • Loy, C. J.; Evelyn, S.; Lim, F. K.; Liu, M. H.; Yong, E. L. Growth Dynamics of Human Leiomyoma Cells and Inhibitory Effects of the Peroxisome Proliferator-Activated Receptor-Gamma Ligand, Pioglitazone. Mol. Hum. Reprod. 2005, 11, 561-566.