Lecturer LIU Mei Hui

(Assistant Dean - Student Life)



BSc (Hons), National University of Singapore, Food Science and Technology, 2003;  Ph.D. , National  University of Singapore (Molecular Biology), 2007; Visiting Fellow, Cornell University, 2010; Postdoctoral Fellow, Genome Institute of Singapore, 2007-2013
A*STAR Graduate Scholar (2004); A*STAR Postdoctoral Fellow (2010)

Contact Information

Office: S14-06-04
Tel: (65)-6516-3523 | Fax: (65)-6779-1691
Email: chmlmh@nus.edu.sg


Recognition and Achievements

  • Faculty Teaching Excellence Award AY2016/2017

 

Research Interests

  • Molecular Nutrition- Diet induced transcription regulation of Nuclear Receptors, their co-regulators and non-coding RNAs in clinically relevant pathways using Genomics and Molecular approaches
  • Nutrigenetics- Modulation of individual susceptibility to insulin resistance
  • Nutrigenomics- Stratified nutritional strategies for the Asian population

 

Teaching Contributions

  • FST2201 Introduction to Human Nutrition
  • FST3202 Nutrition and Disease Prevention
  • FST4202 Advanced Food Processing Technologies
  • GEK1529/GEH1019 Food and Health

 

Representative Publications

  • Lo, K; Huang, S; Walet A.C.E; Zhang, Z; Leow, M.K; Liu, M.H; Sun, L. Adipocyte long noncoding RNA transcriptome analysis of obese mice identified Lnc-leptin which regulates Leptin. Diabetes. 2018; 67(6), 1045-1056.
  • Min A.T.L; Langley S.R; Tan C.F; Fang C.J; Khoo C.M; Leow M.K; Khoo E.Y.H; Moreno Moral A; Pravenec M; Rotival M; Sadananthan S.A; Velan S.S; Venkataraman K; Chong Y.S; Lee Y.S; Sim X; Stunkel W; Liu M.H; Tai E.S; Petretto E. Ethnicity-specific skeletal muscle transcriptional signatures and their relevance to insulin resistance in Singapore. Journal of Clinical Endocrinology and Metabolism. 2018 Aug 21. doi: 10.1210/jc.2018-00309. 
  • Mason, C. E.; Shu, F. J.; Wang, C.; Session, R. M.; Kallen, R. G.; Sidell, N.; Yu, T. W.; Liu, M. H.; Cheung, E.; Kallen, C. B., Location analysis for the estrogen receptor-alpha reveals binding to diverse ERE sequences and widespread binding within repetitive DNA elements. Nucleic Acids Res. 2010, 38 (7), 2355-2368.
  • Fullwood, M. J.; Liu, M. H.; Pan, Y. F. et al., An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 2009, 462 (7269), 58-64.
  • Pan, Y. F.; Wansa Kd; Liu, M. H.; Zhao, B.; Hong, S. Z.; Tan, P. Y.; Lim, K. S.; Bourque, G.; Liu, E. T.; Cheung, E. Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements. J. Biol. Chem. 2008, 283 (47),  32977- 32988 .
  • Yong, E. L.; Li J; Liu, M. H., Single gene contributions: genetic variants of peroxisome proliferator-activated receptor (isoforms alpha, beta/delta and gamma) and mechanisms of dyslipidemias. Curr. Opin. Lipidol. 2008, 19(2), 106- 112.
  • Liu, M.H.; Li, J.; Shen, P.; Tai, E.S.; Yong, E.L., A natural polymorphism in peroxisome proliferator-activated receptor-alpha hinge region attenuates transcription due to defective release of nuclear receptor corepressor from chromatin. Mol. Endocrinol. 2008, 22 (5), 1078-1092.
  • Shen, P.; Liu, M.H.; Ng, T.Y.; Chan, Y.H.; Yong, E.L., Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARα, PPARγ, and adipocyte differentiation in vitro. J. Nutr. 2006, 136(4), 899-905.