Assistant Professor Wu Jie

B.Sc., Beijing Normal University, 2006; Ph.D, Boston University, 2012; Postdoctoral, Massachusetts Institute of Technology, 2012-2015.

Contact Information

Office: S15-05-02
Tel: (65)-6516-1020 | Fax: (65)-6779-1691
Email: | Personal webpage


ORCID: 0000-0002-9865-180X
ResearcherID: C-5504-2016


Recognition and Achievements

  • Young Chemist Award, Department of Chemistry, NUS, 2018
  • Asian Core Program Lectureship Award from China, 2017
  • 4th Green&Sustainable Manufacturing Award, The GSK-Singapore Partnership, 2017
  • SkolTech Postdoctoral Fellow, Massachusetts Institute of Technology, 2013-2014


Research Interests

The research program in WU group have broadly and deeply involved in two research fields of organic synthesis, including photocatalysis and continuous-flow synthesis. My research interests focus on developing green and sustainable chemical synthesis by integrating several novel technologies: i) photocatalysis (clean energy), ii) CH and SiH activation (atom-, step-economic synthesis), iii) natural gas-involved transformation (inexpensive feedstocks), iv) flow technology (sustainable process). Our long-term goal is to advance otherwise difficult or ineffective chemical reactions using advanced flow techniques, as well as to develop new chemical strategies to aid the multistep flow process. Our group’s research is truly multidisciplinary including both organic chemistry and engineering aspects, which provides opportunities to learn areas of research outside of traditional organic synthesis. Students in my group will get trained on photocatalysis, continuous-flow synthesis, multistep synthesis, and green chemistry. They will build indepth chemistry background and strong problem-solving techniques. The advantages of continuous flow processing are increasingly being appreciated both by industry and academia, and students expertized in this field will find enormous job opportunities.


Teaching Contributions

  • CM2121 Organic Chemistry 2
  • CM5221 Advanced Organic Synthesis


Representative Publications 

  • Deng, H. P.; Zhou, Q.; Wu, J. Micro-Tubing Reactor-Assisted Aliphatic C-H Functionalization Utilizing HCl as the Hydrogen Atom Transfer Catalyst Precursor in Conjunction with an Organo Photoredox Catalyst. Angew. Chem. Int. Ed. 2018, 57, 12661-12665.
  • Fan, X.; Rong, J.; Wu, H.; Zhou, Q.; Deng, H.; Tan, J. D.; Xue, C.; Wu, L,; Tao, H.; Wu, J. Eosin Y as a Direct Hydrogen Atom Transfer Photocatalyst for the Functionalization of CH Bonds. Angew. Chem. Int. Ed. 2018, 57, 8514-8518.
  • Hou, J.; Ee, A.; Feng, W.; Xu, J.; Zhao, Y.; Wu, J. Visible-Light-Driven Alkyne Hydro-/Carbocarboxylation Using CO2 via Iridium/Cobalt Dual Catalysis for Divergent Heterocycle Synthesis. J. Am. Chem. Soc. 2018, 140, 5257-5263.
  • Zhou, R.; Goh, Y. Y.; Liu, H.; Tao, H.; Li, L.; Wu, J. Visible-Light-Mediated Metal-Free Hydrosilylation of Alkenes through Selective Hydrogen Atom Transfer for Si-H Activation. Angew. Chem. Int. Ed. 2017, 56, 16621-16625.
  • Deng, H.; Fan, X.; Chen, Z.; Xu, Q.; Wu, J. Photo-Induced Nickel-Catalyzed Chemo- and Regioselective Hydroalkylation of Internal Alkynes with Ether and Amide a-Hetero C(sp3)-H Bonds. J. Am. Chem. Soc. 2017, 139, 13579-13584.
  • Xue, F.; Deng, H.; Xue, C.; Mohamed, D. K. B.; Tang, K. Y.; Wu, J. Reaction Discovery Using Acetylene Gas as the Chemical Feedstock Accelerated by the ‘Stop-Flow’ Micro-Tubing Reactor System. Chem. Sci. 2017, 8, 3623-3627.