Outstanding Chemist Award, Department of Chemistry, NUS, 2017
Thieme Chemistry Journal Award, 2016
Young Scientist Award, Faculty of Science, NUS, 2015
Young Chemist Award, Department of Chemistry, NUS, 2015
To develop simple (asymmetric) catalytic systems to address key problems in chemistry.
Reported the first enantioselective synthesis of ten-membered heterocycles:
CM3221 Organic Synthesis: The Disconnection Approach
Lu, S. et al. Transition Metal-Free Decarboxylative Propargylic Substitution/Cascade Cyclization with Azolium Enolates or Acyl Anions. Angew. Chem. Int. Ed. 2018, 57, 5714.
Wang, Y.-N. et al. Pd-Catalyzed Enantioselective [6+4] Cycloaddition of Vinyl Oxetanes with Azadienes to Access Ten-Membered Heterocycles. Angew. Chem. Int. Ed. 2018, 57, 1596.
Rong, Z. Q. et al. Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis and Rearrangement via Transannular Bond Formation. J. Am. Chem. Soc. 2017, 139, 15304.
Lim, C. S. et al. Enantioselective Synthesis of Tetrahydroquinolines Using Borrowing Hydrogen. Angew. Chem. Int. Ed. 2017, 56, 7176 (VIP article).
Liu, T.-L. et al. Rhodium-Catalyzed Enantioselective Isomerization of Secondary Allylic Alcohols. J. Am. Chem. Soc. 2017, 139, 3643.
Yang, L.-C. et al. Construction of Nine-Membered Heterocycles through Palladium-Catalyzed Formal [5 + 4] Cycloaddition. Angew. Chem. Int. Ed. 2017, 56, 2927.
Huang, Y. et al. Cobalt-Catalyzed Enantioselective Vinylation of Activated Ketones and Imines. J. Am. Chem. Soc. 2016, 138, 6571.
Rong, Z. Q. et al. Dynamic Kinetic Asymmetric Amination of Alcohols: From A Mixture of Four Isomers to Diastereo- and Enantiopure a-Branched Amines. J. Am. Chem. Soc. 2015, 137, 4944.
Zhang, Y. et al. Catalytic Enantioselective Amination of Alcohols by the Use of Borrowing Hydrogen Methodology: Cooperative Catalysis by Iridium and a Chiral Phosphoric Acid. Angew. Chem. Int. Ed. 2014, 53, 1399.